It is nearly Christmas in Pontypandy and Norman is keen to have the best Christmas decorations, which leads to Dilys putting too many into one plug socket, leading to a fire.
Yvette Fielding and the Most Haunted team are in Bolton investigating a building that boasts myriad tales of multiple haunting – including the ghost of Mary, assumed to be the wife of Samuel Crompton (inventor of the Spinning Mule & a former tenant). Visitors report sightings of a peculiar white mist, a grey lady, strange lights, the sound of footsteps and slamming of doors. Children are said to be particularly sensitive to the spirit of a woman named Betty, who apparently shouts at them to leave! With so much unexplained activity what would the Most Haunted investigation of The Hall I’ Th’ Wood bring to light?
Eli and Jordan take on a case to force the government to allow clinical trials of marijuana to cure MS. However, the billionaire philanthropist who backs them soon realizes that his own soon, suffering from MS, doesn't wish to participate. Meanwhile, Maggie and Matt try to determine who the mole is within the new firm that is luring clients to Posner/Kline.
Brenda and Kelly's friendship takes a turn for the worse. Meanwhile, Sean moves in with the Wilson family, Naomi hangs with a new crowd, and Silver becomes jealous when a cheerleader pays a little too much attention to Dixon
While Foreman takes on a pediatric case on his own, the rest of the team deals with a 16-year-old factory manager and emancipated minor who collapses at work. When Foreman's patient takes a turn for the worse, he's forced to question whether he can deal with the situation on his own, or if he needs House's help.
Patrick Jane goes head-to-head with a "psychic" he suspects of murder. Intent on proving the so-called psychic is a fraud -- as well as a killer -- Jane arranges a séance to expose the murderer.
Olivia joins forces with the Strike Team to catch a Mexican drug king and his shipment. Meanwhile, Dutch cleans up Billings' mess, and the death of a woman associated with the Strike Team prompts an investigation by Claudette.
The team searches for a paraplegic who had been injured two years earlier in a car accident and is now missing. Their investigation shocks them when they discover the truth in what may have caused his disappearance.
Some of the world's leading physicists believe they have found startling new evidence showing the existence of universes other than our own. One possibility is that the universe is so vast that an exact replica of our Solar System, our planet and ourselves exists many times over. These Doppelganger Universes exist within our own Universe; in what scientist now call "The Multiverse."
Walter thinks the abduction of a young music prodigy is linked back to his old bunkmate at St. Claire's Hospital. When he kidnaps the child he sees a sequence of flashing lights. Olivia wants Walter to return to the mental institution much to Peter's outcry, but Walter's determination to help ends up having chilling ramifications.
Leonard inadvertently steals away the new woman Wolowitz thinks is the love of his life.
Carl and Denny go to Virginia to defend a prison guard who shot a death-row inmate when a lethal-injection execution was botched. Meanwhile, Alan and Shirley help a woman who says she lost her job after voting for John McCain.
The team needs to acquire a Fulcrum agent list by solving several riddles left behind by Guy Lafleur. Meanwhile, Emmett tries to find out why Chuck is absent so often and goes after his colleagues to get the information.
Charlie's new girlfriend Chelsea asks him to spend the night at her place, which puts Charlie well outside of his comfort zone, while Alan tries to enforce a punishment on Jake initiated by Judith for mooning a group of girls.
Michael races against time and his ailing health to break into the Company headquarters to steal Scylla, but the break-in’s success lies with Sucre. Gretchen dresses up for a meeting with the General and one final attempt to get the last card key. T-Bag must make a decision to leave his criminal ways for good.
A baby is taken from her mother's arms in broad daylight, and the team must race against time to find her.
It's Thanksgiving time and Blair is offended when her Mom's new man hijacks her Thanksgiving traditions. Lily attempts to strengthen the frail bond between Rufus and Jenny. Eric discovers a secret about Bart. Vanessa and Chuck help Nate deal with his father.
Daisy protects Clarabelle's secret recipe for oatmeal raisin cookies from Pete.
A birthday party for one of Lily's co-workers leads to Robin connecting with a group of single partiers known as the "Woo Girls". Ted presents a plan for Goliath National Bank's new HQ.
Sarah finds that the strange dreams she's been having while she sleeps are slowly beginning to creep into her waking life, but she has no idea what the dreams mean for her and John. Derek and Jesse investigate a possible Skynet conspirator.